Dyofertia 10 is a clinically trusted progestogen tablet that contains Dydrogesterone 10mg as its active ingredient. Dydrogesterone is a synthetic progestogen that copies the biological activity of natural progesterone. It is far better tolerated and more bioavailable when taken orally. Dyofertia 10 is a medicine specially made for women’s reproductive health and is widely prescribed across a range of gynaecological and obstetric conditions.
Formulated under WHO-GMP certified manufacturing standards, Dyofertia -10 provides a constant potency and purity in every tablet. The product is designed for easy dosing thus making a good choice for both clinicians and patients.
How Dydrogesterone Works?
Dydrogesterone is a retroprogesterone which implies it is a structural analogue of natural progesterone. It selectively binds to progesterone receptors in the uterus without carrying out any androgenic or glucocorticoid activity. This high receptor selectivity implies it provides specific progestogenic support with a favourable side effect profile.
Upon oral administration, Dydrogesterone transforms the proliferative endometrium into a secretory phase, creating an optimal uterine environment for implantation and the maintenance of early pregnancy. It also exerts immunomodulatory effects that play a role in preventing pregnancy loss associated with immune-related factors.
Therapeutic Indications
Dyofertia-10 (Dydrogesterone 10mg) is indicated for:
- Threatened and habitual (recurrent) miscarriage
- Luteal phase support during ART (Assisted Reproductive Technology) cycles such as IVF and IUI
- Endometriosis to reduce pain and disease progression
- Dysmenorrhoea (painful menstruation)
- Irregular menstrual cycles and secondary amenorrhoea
- Dysfunctional uterine bleeding
- Premenstrual syndrome (PMS)
- Hormone replacement therapy (HRT) as the progestogenic component
Dosage & Administration
The dosage of Dyofertia-10 varies depending on the clinical indication and should always be determined by a qualified gynaecologist or obstetrician. Tablets are taken orally, with or without food, and should be swallowed whole. Typical regimens range from 10mg once daily to 10mg two or three times daily, across specific phases of the menstrual cycle or throughout early pregnancy as directed.
Safety & Tolerability
Dydrogesterone has an established safety profile supported by decades of clinical data. It does not suppress ovulation at standard therapeutic doses, making it suitable for use in women trying to conceive. Unlike many synthetic progestogens, it carries no virilising risk to the foetus and is not associated with significant metabolic side effects. Common and generally mild side effects may include headache, nausea, or breakthrough bleeding, particularly when initiating therapy.
Dyofertia-10 should be used under medical supervision. It is contraindicated in cases of known or suspected progesterone-sensitive cancers, undiagnosed abnormal vaginal bleeding, and hypersensitivity to Dydrogesterone or any excipient.
Why Choose Dyofertia-10 by Aunexis Pharmaceuticals?
- WHO-GMP certified manufacturing for assured quality and safety
- High-purity Dydrogesterone 10mg, consistent potency in every tablet
- Patient-friendly blister packaging for accurate dosing
- Backed by a dedicated gynaecology-focused pharmaceutical team
- Trusted by healthcare professionals across India
Frequently Asked Questions
Q1. What is Dyofertia-10 used for?
Dyofertia-10 is prescribed for threatened miscarriage, recurrent pregnancy loss, endometriosis, irregular periods, dysmenorrhoea, and luteal phase support during fertility treatments.
Q2. What is the active ingredient in Dyofertia-10?
Each tablet contains Dydrogesterone 10mg, a well-studied synthetic progestogen that closely mimics natural progesterone in the body.
Q3. Is Dyofertia-10 safe to use during early pregnancy?
Yes. Dydrogesterone is widely used in early pregnancy under medical supervision to reduce miscarriage risk and support the uterine lining.
Q4. Does Dydrogesterone prevent ovulation?
No. At therapeutic doses, Dydrogesterone does not suppress ovulation, making it suitable for women actively trying to conceive.
Q5. How should Dyofertia-10 tablets be taken?
Tablets are taken orally, with or without food. The dose and duration are determined by your doctor based on your specific condition.
