Gravestat-100 is Aunexis Pharmaceuticals’ branded formulation of Labetalol 100mg, an alpha and beta-adrenergic blocking agent widely prescribed in the management of hypertension. Each Gravestat-100 tablet is manufactured under WHO-GMP certified conditions, ensuring consistent quality, purity and therapeutic reliability in every strip. The product is supplied in a convenient 10×10 strip packing, making it suitable for both retail pharmacy stocking and hospital-based dispensing. Gravestat-100 is also available to distributors and franchise partners across India through Aunexis Pharmaceuticals’ monopoly-based PCD arrangement.
Product Specifications
| Attribute | Details |
| Brand Name | Gravestat-100 |
| Composition | Labetalol 100mg |
| Drug Category | Alpha and Beta-adrenergic Blocker (Antihypertensive) |
| Dosage Form | Tablet |
| Packing | 10×10 Strip |
| Manufacturing Standard | WHO-GMP Certified |
| Storage | Store below 25°C, in a dry place, away from direct sunlight |
| Marketed By | Aunexis Pharmaceuticals |
How Gravestat-100 Works?
Labetalol, the active ingredient in Gravestat-100, is a combined alpha-1 and beta-adrenergic receptor blocker. By blocking alpha-1 receptors, it relaxes and widens blood vessels, reducing resistance to blood flow. At the same time, by blocking beta receptors in the heart, it slows the heart rate and reduces the force of each heartbeat, lowering the heart’s overall workload. Together, these combined actions produce a steady and effective reduction in blood pressure, without the sharp reflex increase in heart rate sometimes seen with medicines that block only beta receptors.
Uses of Gravestat-100
- Management of chronic hypertension (high blood pressure), either alone or alongside other antihypertensive medicines
- Management of hypertensive emergencies in a hospital setting, under close medical supervision
- Management of hypertension during pregnancy, including pre-eclampsia, when specifically prescribed by a treating physician
- Supporting blood pressure control before, during or after certain surgical procedures, as directed by the treating doctor
Gravestat-100 should be used strictly as prescribed. The treating doctor will determine the correct dose, frequency and treatment duration based on the patient’s blood pressure readings, medical history and response to therapy.
Precautions to Be Taken
- Use only under the supervision of a registered medical practitioner; do not self-medicate or adjust the dose without medical advice
- Inform your doctor if you have asthma, bronchospasm, or other respiratory conditions, as beta-blockers can worsen breathing difficulties in some patients
- Inform your doctor if you have a history of heart block, severe bradycardia (slow heart rate), or decompensated heart failure
- Use with caution in patients with liver impairment, as Labetalol is metabolised by the liver
- Diabetic patients should be monitored closely, as beta-blockers can mask some of the warning signs of low blood sugar
- Avoid abrupt discontinuation; stopping treatment suddenly can cause a rebound increase in blood pressure, and the dose should be tapered under medical guidance
- Inform your doctor of all other medicines being taken, including other blood pressure medicines, to avoid potential drug interactions
- Pregnant or breastfeeding women should use Gravestat-100 only when specifically advised by their doctor
- Avoid driving or operating machinery until you know how the medicine affects you, as it may cause dizziness or fatigue in some patients
- Store below 25°C in a dry place, away from direct sunlight and out of reach of children
Frequently Asked Questions
What is Gravestat-100 used for?
It is primarily used for the management of high blood pressure (hypertension). It may also be used in certain hypertensive conditions during pregnancy, strictly under a doctor’s supervision.
How should Gravestat-100 be taken?
Gravestat-100 should only be taken as prescribed by a registered physician. Dosage, frequency and duration vary depending on the patient’s blood pressure levels, medical history and response to treatment.
Is Gravestat-100 available over the counter?
No. Labetalol is a prescription-only medicine. Gravestat-100 should be dispensed only against a valid prescription from a qualified doctor.
What packing does Gravestat-100 come in?
Gravestat-100 is supplied in a 10×10 strip pack, making it convenient for both retail pharmacy and institutional stocking.
Is Gravestat-100 manufactured under quality-certified conditions?
Yes. Gravestat-100 is manufactured by Aunexis Pharmaceuticals under WHO-GMP certified standards, ensuring consistent quality, purity and efficacy in every batch.
Are there any side effects associated with Labetalol?
As with any antihypertensive medication, some patients may experience side effects such as dizziness, fatigue or low blood pressure. Patients should report any unusual symptoms to their prescribing doctor and should never adjust the dose without medical advice.
